heart type fatty acid binding protein rapid test

  • Use of a whole blood rapid panel test for hearttype

    The sensitivity of the rapid hearttype fatty acidbinding protein test was 89% (33/37), significantly higher than for troponin T (22% [8/37]; P<0001) and myoglobin (38% [14/37]; P<0001) However, the specificity of troponin T (94% [29/31]) was significantly better than for hearttype fatty acidbinding protein (52% [16/31]; P= 0002) within 2 hours The area under the receiver operating· Another advantage of the rapid hearttype fatty acid–binding protein test is its superior negative predictive value, which reached 80% (16/20) (vs 50% [29/58] for the troponin T test and 49% [22/45] for the myoglobin test) in patients seen within 2 hours after the onset of symptomsUse of a Whole Blood Panel Test for hearttype· Hearttype fatty acidbinding protein (ELISA) method, which produces results in around 90 minutes, could be overcome by using the new rapid bedside HFABP tests13 However, as it is solely excreted by the kidney, this cardiac marker has limitations in patients with renal impairment and skeletal muscle injury14 Conclusion The main conclusions of this study are, first, that HFABP wasHeartType Fatty AcidBinding Protein in the Early

  • HeartType Fatty AcidBinding Protein Enables

    Seino Y, Tomita Y, Takano T, Ohbayashi K (2004) Office cardiologists cooperative study on whole blood rapid panel tests in patients with suspicious acute myocardial infarction: comparison between hearttype fatty acidbinding protein and troponin T tests , Circ J 68, 14448· To determine the diagnostic accuracy of a rapid hearttype fatty acidbinding protein (HFABP) test in patients suspected of acute coronary syndrome (ACS) in primary care Methods General practitioners included 298 patients suspected of ACS In all patients, whether referred to hospital or not, ECG and cardiac biomarker testing was performed ACS was determined in accordance withDiagnostic value of a hearttype fatty acidbinding· The heart type fatty acid binding protein is a sensitive biomarker for the diagnosis of acute myocardial infarction in the 412 hours of symptom onset when the standard biomarkers may not be elevated, but it is less specific The HFABP assay is not influenced by the age, sex, BP, glycaemic status, BMI and lipid levels of the patient Due to these factors HFABP can be considered as aA Study on the Role of Heart Type Fatty Acid Binding

  • Utility of Hearttype Fatty Acid Binding Protein as a

    · Fatty acidbinding proteins (FABP) are small (15 kDa) cytoplasm proteins that are abundantly expressed in tissues with an active fatty acid metabolism such as heart and liver [7,8] HFABP is found in abundance in cardiomyocytes HFABP is a low molecular weight cytoplasmic protein Because of its small size and location, it is released rapidly into the blood following myocardialRoutinely used biomarkers such as myoglobin, MB form of creatine kinase (CKMB) and cardiac troponinI (cTn I) can be detected at least 3 hours after chest pain and new biomarkers are needed Recent clinical and experimental studies have suggested that hearttype fatty acidbinding protein (HFABP) is superior to CKMB or cardiac troponins in early detection of ischemic myocardial necrosis (1, 2)Value of hearttype fatty acidbinding protein (HFABPThe hearttypeFattyAcidBindingProtein (hFABP) is a protein, which is involved in intracellular myocardial transport (Bruins Slot et al, 2010; Reiter et al, 2013) After myocardial necrosis hFABP is rapidly released into the blood stream and was therefore investigated as a biomarker for AMI However, due to low sensitivity and specificity hFABP has not been proven useful, compared to theHeartType Fatty Acid Binding Protein an overview

  • Pointofcare test of hearttype fatty acidbinding

    · To investigate the efficacies of pointofcare test of hearttype fattyacid binding protein (HFABP) and its combinations with the conventional biomarkers in the diagnosis of early acuteHearttype fatty acidbinding protein (HFABP) may be used as an early marker of AMI due to its high sensitivity, specificity and prognostic value Therefore, in the present study, HFABP was used as a biomarker in a doubleantibody sandwich method and colloidal goldbased lateral flow immunoassay to develop a rapid detection kit for HFABP with a processing time of only 5 min The sensitivity detection of human hearttype fatty acidbindingObjectives: Hearttype fatty acid binding protein (hFABP) is an intracellular molecule engaged in the transport of fatty acids through myocardial cytoplasm and has been used as a rapid marker of myocardial infarction However, its value in the evaluation of perioperative myocardial injury has not yet been assessed Methods: 32 consecutive patients undergoing coronary artery bypass graftingHearttype fatty acid binding protein (hFABP) in the

  • HeartType Fatty AcidBinding Protein Enables Risk

    Seino Y, Tomita Y, Takano T, Ohbayashi K (2004) Office cardiologists cooperative study on whole blood rapid panel tests in patients with suspicious acute myocardial infarction: comparison between hearttype fatty acidbinding protein and troponin T tests , Circ J 68, 14448Hearttype fatty acidbinding protein and myocardial creatine kinase enable rapid risk stratification in normotensive patients with pulmonary embolism Langer M(1), Forkmann M(2), Richter U(1), Tausche AK(1), Sveric K(1), Christoph M(1), Ibrahim K(1), Günther M(1), Kolschmann S(1), Boscheri A(1), Barthel P(1), Strasser RH(1), Wunderlich C(1) Author information: (1)University of TechnologyHearttype fatty acidbinding protein and myocardial· Heart‑type fatty acid‑binding protein (H‑FABP) may be used as an early marker of AMI due to its high sensitivity, specificity and prog‑ nostic value Therefore, in the present study, H‑FABP was used as a biomarker in a double‑antibody sandwich method and colloidal gold‑based lateral flow immunoassay to develop a rapid detection kit for H‑FABP with a processing time of only 5 detection of human heart‑type fatty acid‑binding

  • Diagnostic value of a hearttype fatty acidbinding

    · To determine the diagnostic accuracy of a rapid hearttype fatty acidbinding protein (HFABP) test in patients suspected of acute coronary syndrome (ACS) in primary care Methods General practitioners included 298 patients suspected of ACS In all patients, whether referred to hospital or not, ECG and cardiac biomarker testing was performed ACS was determined in accordance withThe hearttypeFattyAcidBindingProtein (hFABP) is a protein, which is involved in intracellular myocardial transport (Bruins Slot et al, 2010; Reiter et al, 2013) After myocardial necrosis hFABP is rapidly released into the blood stream and was therefore investigated as a biomarker for AMI However, due to low sensitivity and specificity hFABP has not been proven useful, compared to theHeartType Fatty Acid Binding Protein an overviewThe sensitivity of the rapid hearttype fatty acid–binding protein test was 89% (33/37), significantly higher than for troponin T (22% [8/37]; P<0001) and myoglobin (38% [14/37]; P<0001) However, the specificity of troponin T (94% [29/31]) was significantly better than for hearttype fatty acid–binding protein (52% [16/31]; P= 0002) within 2 hours The area under the receiver operatingUse of a Whole Blood Panel Test for hearttype fatty

  • Development of an Ultra Diagnostic Method Based on

    · Hiura M, Nakajima O, Mori T, Kitano K (2005) Performance of a semiquantitative whole blood test for human hearttype fatty acidbinding protein (HFABP) Clin Biochem 38:948–950 CAS Article PubMed Google Scholar Laemmli UK (1970) Cleavage of structural proteins during the assembly of bacteriophage T4 Nature 227:680–0401· Hearttype fatty acid binding protein (HFABP) is a low molecular weight protein (15 kDa)[12], which mainly MENG FanDa et al / Chinese Journal of Analytical Chemistry, 2016, 44(4): 633–639 responsible for combining with fatty acids and regulating cell metabolism As the specific protein presented in the cytoplasm of myocardial cells, HFABP can be released into the blood in theA Microfluidic Fluorescence Immunoassay Test Card for· Heart‑type fatty acid‑binding protein (H‑FABP) may be used as an early marker of AMI due to its high sensitivity, specificity and prognostic value Therefore, in the present study, H‑FABP was used as a biomarker in a double‑antibody sandwich method and colloidal gold‑based lateral flow immunoassay to develop a rapid detection kit for H‑FABP with a processing time of only 5 min detection of human heart‑type fatty acid‑binding

  • Hearttype fatty acidbinding protein in the early

    Use of a whole blood rapid panel test for hearttype fatty acidbinding protein in patients with acute chest pain: comparison with rapid troponin T and myoglobin tests Am J Med 2003; 115: 185 – 90Use of a whole blood rapid panel test for hearttype fatty acidbinding protein in patients with acute chest pain: comparison with rapid troponin T and myoglobin tests Am J Med 2003; 115: 185 – 90BET 2 HEART FATTY ACID BINDING PROTEIN FOR RAPID· Hearttype fatty acid–binding protein (HFABP), which is associated with fatty acid metabolism, is a lowmolecularweight (15 kDa) cytoplasmic protein that is rapidly released into the circulation following myocardial necrosis 6 Therefore, it is thought to be a sensitive marker for the early diagnosis of AMI 8, 11–13 HFABP is more strongly expressed in cardiac muscle than in skeletalAutomated HeartType Fatty Acid–Binding Protein Assay for

  • Hearttype fatty acid binding protein (hFABP) in the

    · Abstract Objectives: Hearttype fatty acid binding protein (hFABP) is an intracellular molecule engaged in the transport of fatty acids through myocardial cytoplasm and has been used as a rapid marker of myocardial infarctionHowever, its value in the evaluation of perioperative myocardial injury has not yet been assessed Methods: 32 consecutive patients undergoing coronary arteryHigh quality Heart Type Fatty Acid Binding Protein HFABP Test 201200ng/ML from China, China's leading heart type fatty acid binding protein test product, with strict quality control 1200ng/ML HFABP Test factories, producing high quality HFABP rapid ag test kit productsHeart Type Fatty Acid Binding Protein HFABP Test 2Background: To determine the diagnostic accuracy of a rapid hearttype fatty acidbinding protein (HFABP) test in patients suspected of acute coronary syndrome (ACS) in primary care Methods: General practitioners included 298 patients suspected of ACS In all patients, whether referred to hospital or not, ECG and cardiac biomarker testing was performed ACS was determined in accordance withDiagnostic value of a hearttype fatty acidbinding

  • Pointofcare test of hearttype fatty acidbinding

    Unbound free fatty acids and hearttype fatty acidbinding protein: diagnostic assays and clinical applications Clin Chem 2006; 52:19–29 Arimoto T, Takeishi Y, Shiga R, Fukui A, Tachibana H, Nozaki N, et al Prognostic value of elevated circulating hearttype fatty acid binding protein in patients with congestive heart failureFatty acidbinding protein (FABP) is an independent predictor of cardiac events However, the relation between increasing FABP and coronary atherosclerosis is unknown We have investigated the relation between FABP and angiographic properties of coronary atherosclerosis in patients with acute coronary syndrome (ACS) The study population consisted of 93 patients with ACS (mean age: 56±10The role of hearttype fatty acidbinding protein in· The serum hearttype fatty acidbinding protein (sHFABP) level was measured within 10 min of admission The patients were assigned to intensive care (n = 835) or other departments (n = 171) The intensive care patients were divided into survivors (n = 745) and nonsurvivors (n = 90) according to the inhospital mortality and assigned to four groups according to the quartiles of sHPrognostic impact of the serum hearttype fatty acid

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